It is highly soluble in water (1:0.7) and in alcohol (1:1.5). It is an amide-type local anesthetic with a rapid onset and an intermediate duration of action. Lidocaine HCl (C 14H 22N 2O.HCl.H 2O, MW 288.81) occurs as a white, odorless, crystalline powder with a slightly bitter taste. It elicits mild anesthetic properties when used topically. Diphenhydramine HCl is freely soluble in water and in alcohol. It slowly darkens on exposure to light, and its solutions are practically neutral. The 119-mL size of the compounded preparation contains diphenhydramine HCl 0.1 g, lidocaine HCl 0.8 g, and FIRST Mouthwash Suspension 118 mL.ĭiphenhydramine HCl (C 17H 21NO.HCl, MW 291.82), an H 1-receptor antagonist used for the relief of hypersensitivity reactions, occurs as a white, odorless, crystalline powder.
NYSTATIN SWISH AND SWALLOW DIRECTIONS PLUS
The Mouthwash BLM Compounding Kit contains premeasured diphenhydramine HCl powder, lidocaine HCl powder, and mouthwash suspension (aluminum hydroxide, magnesium hydroxide, and simethicone, plus inactive ingredients). 2ĭiscussion: This formula is equivalent to the active ingredients in compounded Magic Mouthwash. Quality Control: Quality-control assessment can include weight/volume, pH, specific gravity, active drug assay, color, rheologic properties, physical observation, and physical stability (discoloration, foreign materials, gas formation, mold growth). Stability: Based on real-time controlled room temperature and humidity testing, the finished, compounded Mouthwash BLM Compounding product is stable for at least 180 days. Packaging: Package in the container in which it is provided and compounded. Use: This preparation is used to ease mucositis symptoms caused by some forms of chemotherapy and radiation therapy, as well as for aphthous ulcers, other oral ulcers, and other mouth pain. Residual quantities remaining in the bottles after emptying need not be rinsed out. The appropriate quantities of diphenhydramine HCl powder and lidocaine HCl powder have been packaged in each bottle to deliver the required dose of each drug.
Close the suspension bottle and vigorously shake it vertically for approximately 20 to 30 seconds. Because of the hygroscopic nature and small volume of the powder, use the enclosed spatula to empty the contents into the mouthwash suspension. Likewise, tap the top and bottom of the diphenhydramine HCl bottle. Open the suspension bottle and empty the lidocaine HCl powder into the suspension.
Before compounding, tap the top and bottom of the lidocaine hydrochloride (HCl) bottle. Accurately weigh or measure each ingredient. Method of Preparation: Calculate the quantity of each ingredient for the amount to be prepared.
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